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Comprehending how diet plan impacts tumour development might cause much better treatments. Analysis in mice exposes that a low-calorie diet plan, however not a ketogenic diet plan, slows the development of pancreatic cancer. This impact is moderated by lipid modifications.
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Giulia Salvadori
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Giulia Salvadori is at the IFOM, FIRC Institute of Molecular Oncology, Milan 20139, Italy, and in the Department of Oncology and Hemato-oncology, University of Milan.
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Valter D. Longo
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Valter D. Longo is at the IFOM, FIRC Institute of Molecular Oncology, Milan 20139, Italy, and in the Longevity Institute and Davis School of Gerontology, University of Southern California, Los Angeles, California, USA.
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Various diet plans, such as those that occasionally limit calorie consumption and therefore drive metabolic modifications connected with fasting (regular fasting-mimicking diet plans) 1, or ones that are low in carbs and high in fat (ketogenic diet plans), are becoming dietary interventions that can postpone cancer development and possibly improve the impact of anticancer drugs 1, 2 Whereas long-lasting calorie limitation is not practical for individuals on the majority of cancer treatments since it causes weight reduction and lean body mass 3, ketogenic diet plans and routine fasting-mimicking diet plans are starting to be checked in a series of scientific trials, and are especially appealing when utilized in mix with basic treatments 1, 2, 4— 6 Composing in Nature, Lien et al 7 fill in a few of the missing out on information about how diet plan impacts cancer development.
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doi: https://doi.org/101038/ d41586-021-02775 -1
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Competing Interests
V.D.L. has equity interest in L-Nutra, a business that produces medical food. He does not get speaking with costs from L-Nutra and has actually devoted 100%of his shares to charity.
